I suppose this should be adressed to native English speakers.
I just read in an article by a respected linguist that it is kind of unacceptable to say, 'you are wrong'. Well, in my language and my culture (i.e. Russian) there is a much-used phrase, ты неправ(-а), which literally translates as 'you are not right' (there is no word for 'wrong' other than that) but really works as something like 'I think what you just said is wrong' or 'I disagree with what you just said' and is a perfectly acceptable way to start or mark an objection. For all I know, nobody ever gets offended by that. So, would you really feel hurt if somebody bluntly told you 'you are wrong' in a conversation, and how often does it happen at all?